After almost four years of development, experimentation, and knowledge building on clinical implementation of precision medicine, we conclude BigMed with this final report, Reflections on the clinical implementation of precision medicine - Experiences from BigMed, a Norwegian ICT Lighthouse project. The report summarizes experiences and reflections from this unique cross sector and cross competence project and is meant to be a guide for subsequent projects on the implementation of precision medicine. Participants from the project have contributed through discussions, deliverables and knowledge summaries, resulting in a report that includes perspectives, reflections and wisdom from a broad consortium. The content covers both visions and future goals, as well as practical examples of solutions made in the project. The 2018 BigMed position paper, Big data management for the precise treatment of three patient groups, which identified the initial barriers to clinical implementation of precision medicine, was the starting point for the project. The 2021 report follows from this to conclude on the experiences made through the project. Check out bigmed.no for more information!
Dr Davit Aghayan is a young surgeon who defended his thesis Laparoscopic parenchyma-sparing surgery in the treatment of colorectal liver metastasis on December 14th 2020 on clinical material from The Intervention Centre. It turns out the his thesis is number 5000 at Faculty of Medicine at University of Oslo. This milestone was celebrated on April 29 at Oslo University Hospital. Dr Aghayan received a gift from the faculty's pro dean for research Jens Petter Berg. The main supervisor professor Bjørn Edwin was also part of the ceremony outside Oslo University Hospital . The high number of dissertations underpins the strong position of the faculty in research and research education. Around 200 dissertations are produced annually. Read more at UiO's website.
On March 15 2021 Master of valuebased leadership Kjersti Wendt at Institute of Clinical Medicine defended a on thesis Vascular Disease Management: Knowledge Development and the Politics of Organizational Adaptation for the degree of PhD (Philosophiae Doctor). Adjudication committee
First opponent: Professor Emeritus Mats Brommels, Karolinska Institute, Stockholm, Sweden. Second opponent: Adjunct Professor Rebecka Hultgren, Karolinska Institute, Stockholm, Sweden. Third member and chair of the evaluation committee: Professor Kristin Margrete Heggen, Institute of Health and Society, University of Oslo. Chair of defence
Professor II Marit Lieng, Institute of Clinical Medicine, University of Oslo. Principal Supervisor Professor II Erik Fosse, Institute of Clinical Medicine, University of Oslo
MSc Pengfei Lu successfully defended his PhD thesis "Cardiomyocyte Communication for Heart Applications" at the Faculty of Medicine, University of Oslo on March 4, 2021.
In his thesis he investigated and established a novel strategy for energy efficient stimulation (pacing) and digital data transfer (cell-to-cell communication) using cardiomyocytes, which could be consider for the development of biological pacemakers.
The PhD assessment committee consisted of Professor Robert Schober, Friedrich-Alexander University of Erlangen-Nuremberg, Germany, Senior Researcher Valeria Loscri, Inria Lille-Nord Europe, France, and Professor Farrukh Abbas Chaudhry, Institute of Basic Medical Sciences, University of Oslo.
Pengfei Lu was supervised by Professor Ilangko Balasingham, Professor Erik Fosse, Professor Per Steinar Halvorsen, and Dr. Jacob Bergsland at the Intervention Centre, Oslo University Hospital.
After almost four years of development, experimentation and knowledge building on clinical implementation of precision medicine, participants from the lighthouse project BigMed demonstrate selected solutions established in the project.
Video of BigMed at EHiN 2020 is available HERE
Streamlining pipelines for genomic analyzes and making information available to oncologists who are to make decisions about the patient are some of the many areas where BigMed has developed proposals for technical solutions.
The solutions presented are: